Serveur d'exploration sur le patient édenté

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Nicorandil can induce severe oral ulceration

Identifieur interne : 008939 ( Main/Exploration ); précédent : 008938; suivant : 008940

Nicorandil can induce severe oral ulceration

Auteurs : Crispian Scully ; Antonio Mano Azul ; Alexander Crighton ; David Felix ; Anne Field ; Stephen R. Porter

Source :

RBID : ISTEX:577EE3918EF776A8D8061E663F0E81F8C1CC987A

Descripteurs français

English descriptors

Abstract

Abstract: Objective: To increase physicians’ and dentists’ awareness that nicorandil is a potential inducer of severe mouth ulceration. Study Design: Nine new cases of ulceration from 3 European countries were included in this study. Results: Oral ulceration developed within 9 months of beginning nicorandil therapy, and ulcers resolved within 1 month of withdrawal of the drug. No lesions developed on other epithelia. Conclusions: A number of drugs used in the care of patients with cardiovascular disease can cause oral adverse effects. Nicorandil, a new potassium-channel activator used in some countries to treat angina pectoris, precipitates persistent ulcerative stomatitis in some patients. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001;91:189-93)

Url:
DOI: 10.1067/moe.2001.110306


Affiliations:


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Le document en format XML

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<div type="abstract" xml:lang="en">Abstract: Objective: To increase physicians’ and dentists’ awareness that nicorandil is a potential inducer of severe mouth ulceration. Study Design: Nine new cases of ulceration from 3 European countries were included in this study. Results: Oral ulceration developed within 9 months of beginning nicorandil therapy, and ulcers resolved within 1 month of withdrawal of the drug. No lesions developed on other epithelia. Conclusions: A number of drugs used in the care of patients with cardiovascular disease can cause oral adverse effects. Nicorandil, a new potassium-channel activator used in some countries to treat angina pectoris, precipitates persistent ulcerative stomatitis in some patients. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001;91:189-93)</div>
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